What Repeated Blast Exposure Does to the Brain
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Understanding the Neurobiological Impact in Veterans

Traumatic brain injury (TBI) is often associated with a single identifiable event. However, emerging research suggests that repeated low-level blast exposure, common in military training and operational environments, may result in measurable neurological changes even in the absence of a diagnosed concussion.
A study by Melissa Hunfalvay and colleagues (2022) examined the long-term effects of repeated blast exposure and high-caliber weapons use in military special operators. Their findings provide important insight into how subtle, cumulative exposures may influence brain function over time.
Study Overview ; Long-Term Effects of Low-Level Blast Exposure and High-Caliber Weapons Use in Military Special Operators
The study evaluated special operations military personnel with a history of repeated exposure to:
• low-level blasts (e.g., breaching activities)
• high-caliber weapons use
Participants underwent:
• oculomotor (eye-tracking) testing
• symptom-based concussion assessments
These results were compared to those of individuals without similar exposure histories.
Key Findings
Disruption in Oculomotor Function
Participants with repeated blast exposure demonstrated measurable impairments in eye movement, including:
• reduced tracking accuracy
• increased variability in eye movements
• difficulty maintaining visual focus
• slowed response during tracking tasks
Oculomotor function is closely tied to brain network coordination, attention, and processing speed, making it a useful indicator of neurological efficiency.
Correlation with Physical and Cognitive Symptoms
Impaired eye-tracking performance was associated with:
• headaches
• dizziness
• light sensitivity
• balance disturbances
• cognitive complaints
These findings suggest that objective neurological changes align with commonly reported symptoms, even when a formal TBI diagnosis is not present.
Evidence of Subclinical Neurological Impact
Importantly, many individuals in the study did not meet criteria for a diagnosed concussion, yet still demonstrated measurable changes in brain function.
This supports the concept that:
Repeated low-level exposure doesn’t have to cause a single injury to change how the brain functions over time.
Real-World Presentation
In clinical settings, these patterns may present as:
• slowed cognitive processing
• difficulty tracking conversations
• irritability or emotional reactivity
• mental fatigue or overstimulation
• visual strain or headaches
• a persistent sense of not feeling “sharp”
These symptoms are often interpreted as purely psychological, but may reflect underlying neurobiological inefficiencies.
Impact on Daily Functioning
Oculomotor and brain network disruptions can influence:
• reading and screen tolerance
• driving and reaction time
• work performance and task completion
• balance and spatial awareness
• emotional regulation
These effects can significantly impact quality of life, particularly in individuals transitioning from high-demand operational environments.
Clinical Implications
This research highlights the importance of:
• objective assessment of brain function
• recognition of subclinical neurological changes
• understanding the interaction between brain function and symptom presentation
Traditional symptom-based approaches may not fully capture the complexity of these cases.
Application in Clinical Practice
At Brain Treatment Center NoVA, we frequently work with individuals presenting with similar patterns.
Within our clinical framework, we may:
• review brain mapping data (qEEG) to better understand functional patterns
• discuss laboratory findings provided by the medical team and explore potential connections to mood, cognition, and regulation
• support interventions aimed at improving brain regulation and nervous system function
• collaborate with medical providers to address physiological contributors to symptoms
This allows for a more comprehensive, individualized understanding of each patient’s presentation.
Conclusion
The findings from this study contribute to a growing body of evidence indicating that:
repeated blast exposure can impact brain function even in the absence of a diagnosed TBI
For many veterans, this helps explain persistent symptoms that have not been fully understood or addressed.
Recognizing the role of cumulative exposure and neurobiological function is an important step toward developing more effective, individualized approaches to care.
References
Hunfalvay, M., Murray, N. P., Creel, W. T., & Carrick, F. R. (2022).
Long-term effects of low-level blast exposure and high-caliber weapons use in military special operators. Brain Sciences, 12(5), 601.




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